Retrospective observational study about reducing the false negative rate of the sentinel lymph node biopsy
Identifieur interne : 000214 ( Main/Exploration ); précédent : 000213; suivant : 000215Retrospective observational study about reducing the false negative rate of the sentinel lymph node biopsy
Auteurs : Yu-Ting Zhou ; Zheng-Gui Du [République populaire de Chine] ; Di Zhang ; Qing LvSource :
- Medicine [ 0025-7974 ] ; 2017.
Abstract
Reducing the false negative rate of sentinel lymph node biopsy (SLNB) for breast cancer patients has always been a focus of clinical research. We aimed to map the sentinel lymph nodes (SLNs) in detail, and analyze the factors related to SLNs located at locations that are often ignored by surgeons, to reduce the rate of false negatives from SLNB. A retrospective analysis involving 545 breast cancer patients who underwent SLNB in west China hospital between August 2010 and February 2016 was performed. Blue dye, radioisotope, or combined methods were used for tracing SLNs. Using blue dye, radioisotope, and a combination of blue dye and radioisotope successfully traced SLNs in 479, 507, and 525 patients, the detection rate was 88.2%, 93.9%, and 97.4%, respectively. Among the 1559 detected SLNs, 139 (9.6%) were located at the latissimus dorsi lateral margin, and 108 (6.9%) were located at level 2. Subcutaneous injection of radioisotope (
Url:
DOI: 10.1097/MD.0000000000007787
PubMed: 28834882
PubMed Central: 5572004
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 004204
- to stream Pmc, to step Curation: 004203
- to stream Pmc, to step Checkpoint: 000098
- to stream Ncbi, to step Merge: 009411
- to stream Ncbi, to step Curation: 009411
- to stream Ncbi, to step Checkpoint: 009411
- to stream Main, to step Merge: 000214
- to stream Main, to step Curation: 000214
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Retrospective observational study about reducing the false negative rate of the sentinel lymph node biopsy</title>
<author><name sortKey="Zhou, Yu Ting" sort="Zhou, Yu Ting" uniqKey="Zhou Y" first="Yu-Ting" last="Zhou">Yu-Ting Zhou</name>
<affiliation><nlm:aff id="aff1">Department of Breast Surgery</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff2">Laboratory of Breast Disease</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Du, Zheng Gui" sort="Du, Zheng Gui" uniqKey="Du Z" first="Zheng-Gui" last="Du">Zheng-Gui Du</name>
<affiliation><nlm:aff id="aff1">Department of Breast Surgery</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff2">Laboratory of Breast Disease</nlm:aff>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff3">Laboratory of Pathology, West China Hospital, Sichuan University, Chengdu, China.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country>
<wicri:regionArea>Laboratory of Pathology, West China Hospital, Sichuan University, Chengdu</wicri:regionArea>
<wicri:noRegion>Chengdu</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Zhang, Di" sort="Zhang, Di" uniqKey="Zhang D" first="Di" last="Zhang">Di Zhang</name>
<affiliation><nlm:aff id="aff1">Department of Breast Surgery</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff2">Laboratory of Breast Disease</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Lv, Qing" sort="Lv, Qing" uniqKey="Lv Q" first="Qing" last="Lv">Qing Lv</name>
<affiliation><nlm:aff id="aff1">Department of Breast Surgery</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff2">Laboratory of Breast Disease</nlm:aff>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">28834882</idno>
<idno type="pmc">5572004</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572004</idno>
<idno type="RBID">PMC:5572004</idno>
<idno type="doi">10.1097/MD.0000000000007787</idno>
<date when="2017">2017</date>
<idno type="wicri:Area/Pmc/Corpus">004204</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">004204</idno>
<idno type="wicri:Area/Pmc/Curation">004203</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">004203</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000098</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000098</idno>
<idno type="wicri:Area/Ncbi/Merge">009411</idno>
<idno type="wicri:Area/Ncbi/Curation">009411</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">009411</idno>
<idno type="wicri:doubleKey">0025-7974:2017:Zhou Y:retrospective:observational:study</idno>
<idno type="wicri:Area/Main/Merge">000214</idno>
<idno type="wicri:Area/Main/Curation">000214</idno>
<idno type="wicri:Area/Main/Exploration">000214</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Retrospective observational study about reducing the false negative rate of the sentinel lymph node biopsy</title>
<author><name sortKey="Zhou, Yu Ting" sort="Zhou, Yu Ting" uniqKey="Zhou Y" first="Yu-Ting" last="Zhou">Yu-Ting Zhou</name>
<affiliation><nlm:aff id="aff1">Department of Breast Surgery</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff2">Laboratory of Breast Disease</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Du, Zheng Gui" sort="Du, Zheng Gui" uniqKey="Du Z" first="Zheng-Gui" last="Du">Zheng-Gui Du</name>
<affiliation><nlm:aff id="aff1">Department of Breast Surgery</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff2">Laboratory of Breast Disease</nlm:aff>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff3">Laboratory of Pathology, West China Hospital, Sichuan University, Chengdu, China.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country>
<wicri:regionArea>Laboratory of Pathology, West China Hospital, Sichuan University, Chengdu</wicri:regionArea>
<wicri:noRegion>Chengdu</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Zhang, Di" sort="Zhang, Di" uniqKey="Zhang D" first="Di" last="Zhang">Di Zhang</name>
<affiliation><nlm:aff id="aff1">Department of Breast Surgery</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff2">Laboratory of Breast Disease</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Lv, Qing" sort="Lv, Qing" uniqKey="Lv Q" first="Qing" last="Lv">Qing Lv</name>
<affiliation><nlm:aff id="aff1">Department of Breast Surgery</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff2">Laboratory of Breast Disease</nlm:aff>
</affiliation>
</author>
</analytic>
<series><title level="j">Medicine</title>
<idno type="ISSN">0025-7974</idno>
<idno type="eISSN">1536-5964</idno>
<imprint><date when="2017">2017</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><title>Abstract</title>
<p>Reducing the false negative rate of sentinel lymph node biopsy (SLNB) for breast cancer patients has always been a focus of clinical research. We aimed to map the sentinel lymph nodes (SLNs) in detail, and analyze the factors related to SLNs located at locations that are often ignored by surgeons, to reduce the rate of false negatives from SLNB. A retrospective analysis involving 545 breast cancer patients who underwent SLNB in west China hospital between August 2010 and February 2016 was performed. Blue dye, radioisotope, or combined methods were used for tracing SLNs. Using blue dye, radioisotope, and a combination of blue dye and radioisotope successfully traced SLNs in 479, 507, and 525 patients, the detection rate was 88.2%, 93.9%, and 97.4%, respectively. Among the 1559 detected SLNs, 139 (9.6%) were located at the latissimus dorsi lateral margin, and 108 (6.9%) were located at level 2. Subcutaneous injection of radioisotope (<italic>P</italic>
<italic>=</italic>
.004) and intradermal injection of blue dye (<italic>P</italic>
<italic>=</italic>
.002) were independent factors associated with SLNs distributed at level 2 and the latissimus dorsi lateral margin, respectively. It was noteworthy that 2 of 7 patients had skipping metastasis in level 2, so subcutaneous injection of the isotope is strongly recommended for tracing SLNs distributed in level 2 because of the possibility of skipping metastasis. Though intradermal injection of blue dye was superior methods for tracing SLNs located at the latissimus dorsi lateral margin, we surprisingly found those patients with metastasis to the latissimus dorsi lateral margin nodes also could have metastasis to level 1 (expect for the latissimus dorsi lateral margin) nodes, it seemed that maybe there is no need to excise SLNs at the latissimus dorsi lateral margin in SLNB, whether such nodes should be regarded as useful for SLNB still needs to be determined by further large, multicenter clinical studies.</p>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Dixon, Jm" uniqKey="Dixon J">JM Dixon</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bao, J" uniqKey="Bao J">J Bao</name>
</author>
<author><name sortKey="Donovan, C" uniqKey="Donovan C">C Donovan</name>
</author>
<author><name sortKey="Chung, A" uniqKey="Chung A">A Chung</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bao, J" uniqKey="Bao J">J Bao</name>
</author>
<author><name sortKey="Giuliano, Ae" uniqKey="Giuliano A">AE Giuliano</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Liu, M" uniqKey="Liu M">M Liu</name>
</author>
<author><name sortKey="Wang, S" uniqKey="Wang S">S Wang</name>
</author>
<author><name sortKey="Cui, S" uniqKey="Cui S">S Cui</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Beek, Ma" uniqKey="Beek M">MA Beek</name>
</author>
<author><name sortKey="Verheuvel, Nc" uniqKey="Verheuvel N">NC Verheuvel</name>
</author>
<author><name sortKey="Luiten, Ej" uniqKey="Luiten E">EJ Luiten</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Doscher, Me" uniqKey="Doscher M">ME Doscher</name>
</author>
<author><name sortKey="Schreiber, Je" uniqKey="Schreiber J">JE Schreiber</name>
</author>
<author><name sortKey="Weichman, Ke" uniqKey="Weichman K">KE Weichman</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Coromilas, Ej" uniqKey="Coromilas E">EJ Coromilas</name>
</author>
<author><name sortKey="Wright, Jd" uniqKey="Wright J">JD Wright</name>
</author>
<author><name sortKey="Huang, Y" uniqKey="Huang Y">Y Huang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lyman, Gh" uniqKey="Lyman G">GH Lyman</name>
</author>
<author><name sortKey="Temin, S" uniqKey="Temin S">S Temin</name>
</author>
<author><name sortKey="Edge, Sb" uniqKey="Edge S">SB Edge</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Jakobsen, Jk" uniqKey="Jakobsen J">JK Jakobsen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="James, Ta" uniqKey="James T">TA James</name>
</author>
<author><name sortKey="Coffman, Ar" uniqKey="Coffman A">AR Coffman</name>
</author>
<author><name sortKey="Chagpar, Ab" uniqKey="Chagpar A">AB Chagpar</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Nieciecki, M" uniqKey="Nieciecki M">M Nieciecki</name>
</author>
<author><name sortKey="Dobruch Sobczak, K" uniqKey="Dobruch Sobczak K">K Dobruch-Sobczak</name>
</author>
<author><name sortKey="Wareluk, P" uniqKey="Wareluk P">P Wareluk</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Nowikiewicz, T" uniqKey="Nowikiewicz T">T Nowikiewicz</name>
</author>
<author><name sortKey="Kurylcio, A" uniqKey="Kurylcio A">A Kurylcio</name>
</author>
<author><name sortKey="Polkowski, W" uniqKey="Polkowski W">W Polkowski</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bakhtiar, N" uniqKey="Bakhtiar N">N Bakhtiar</name>
</author>
<author><name sortKey="Jaleel, F" uniqKey="Jaleel F">F Jaleel</name>
</author>
<author><name sortKey="Moosa, Fa" uniqKey="Moosa F">FA Moosa</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="He, Ps" uniqKey="He P">PS He</name>
</author>
<author><name sortKey="Li, F" uniqKey="Li F">F Li</name>
</author>
<author><name sortKey="Li, Gh" uniqKey="Li G">GH Li</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Toh, U" uniqKey="Toh U">U Toh</name>
</author>
<author><name sortKey="Iwakuma, N" uniqKey="Iwakuma N">N Iwakuma</name>
</author>
<author><name sortKey="Mishima, M" uniqKey="Mishima M">M Mishima</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Shinden, Y" uniqKey="Shinden Y">Y Shinden</name>
</author>
<author><name sortKey="Ueo, H" uniqKey="Ueo H">H Ueo</name>
</author>
<author><name sortKey="Tobo, T" uniqKey="Tobo T">T Tobo</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wu, X" uniqKey="Wu X">X Wu</name>
</author>
<author><name sortKey="Lin, Q" uniqKey="Lin Q">Q Lin</name>
</author>
<author><name sortKey="Chen, G" uniqKey="Chen G">G Chen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wang, X" uniqKey="Wang X">X Wang</name>
</author>
<author><name sortKey="Yang, Z" uniqKey="Yang Z">Z Yang</name>
</author>
<author><name sortKey="Lin, B" uniqKey="Lin B">B Lin</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Maguire, A" uniqKey="Maguire A">A Maguire</name>
</author>
<author><name sortKey="Brogi, E" uniqKey="Brogi E">E Brogi</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Tallet, A" uniqKey="Tallet A">A Tallet</name>
</author>
<author><name sortKey="Lambaudie, E" uniqKey="Lambaudie E">E Lambaudie</name>
</author>
<author><name sortKey="Cohen, M" uniqKey="Cohen M">M Cohen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Li, Cz" uniqKey="Li C">CZ Li</name>
</author>
<author><name sortKey="Zhang, P" uniqKey="Zhang P">P Zhang</name>
</author>
<author><name sortKey="Li, Rw" uniqKey="Li R">RW Li</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ngui, Nk" uniqKey="Ngui N">NK Ngui</name>
</author>
<author><name sortKey="French, J" uniqKey="French J">J French</name>
</author>
<author><name sortKey="Kilby, Cj" uniqKey="Kilby C">CJ Kilby</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Tanaka, T" uniqKey="Tanaka T">T Tanaka</name>
</author>
<author><name sortKey="Sato, S" uniqKey="Sato S">S Sato</name>
</author>
<author><name sortKey="Tada, A" uniqKey="Tada A">A Tada</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Han, C" uniqKey="Han C">C Han</name>
</author>
<author><name sortKey="Yang, B" uniqKey="Yang B">B Yang</name>
</author>
<author><name sortKey="Zuo, Ws" uniqKey="Zuo W">WS Zuo</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Clough, Kb" uniqKey="Clough K">KB Clough</name>
</author>
<author><name sortKey="Nasr, R" uniqKey="Nasr R">R Nasr</name>
</author>
<author><name sortKey="Nos, C" uniqKey="Nos C">C Nos</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kang, B" uniqKey="Kang B">B Kang</name>
</author>
<author><name sortKey="Jun, H" uniqKey="Jun H">H Jun</name>
</author>
<author><name sortKey="Lee, K" uniqKey="Lee K">K Lee</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Han, C" uniqKey="Han C">C Han</name>
</author>
<author><name sortKey="Yang, L" uniqKey="Yang L">L Yang</name>
</author>
<author><name sortKey="Zuo, W" uniqKey="Zuo W">W Zuo</name>
</author>
</analytic>
</biblStruct>
</listBibl>
</div1>
</back>
</TEI>
<affiliations><list><country><li>République populaire de Chine</li>
</country>
</list>
<tree><noCountry><name sortKey="Lv, Qing" sort="Lv, Qing" uniqKey="Lv Q" first="Qing" last="Lv">Qing Lv</name>
<name sortKey="Zhang, Di" sort="Zhang, Di" uniqKey="Zhang D" first="Di" last="Zhang">Di Zhang</name>
<name sortKey="Zhou, Yu Ting" sort="Zhou, Yu Ting" uniqKey="Zhou Y" first="Yu-Ting" last="Zhou">Yu-Ting Zhou</name>
</noCountry>
<country name="République populaire de Chine"><noRegion><name sortKey="Du, Zheng Gui" sort="Du, Zheng Gui" uniqKey="Du Z" first="Zheng-Gui" last="Du">Zheng-Gui Du</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000214 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000214 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= LymphedemaV1 |flux= Main |étape= Exploration |type= RBID |clé= PMC:5572004 |texte= Retrospective observational study about reducing the false negative rate of the sentinel lymph node biopsy }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:28834882" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \ | NlmPubMed2Wicri -a LymphedemaV1
This area was generated with Dilib version V0.6.31. |